Description

2-[[(5-Methyl-1H-Imidazol-4-Yl)Methyl]Thio]Ethylamine Dihydrochloride is a high-purity, functionalized imidazole derivative of significant interest in advanced organic synthesis. This compound matters for its role as a versatile pharmacological intermediate and a key building block in the development of novel bioactive molecules. Pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers need it to create compounds targeting specific biological pathways, leveraging its unique sulfur-containing side chain for molecular diversification.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of histamine H3 receptor antagonists and other neuroactive agents.
• Agrochemical Research: Used in developing novel fungicides and plant growth regulators due to its imidazole core structure.
• Bioconjugation & Probe Synthesis: The amine and thioether functional groups make it suitable for creating fluorescent probes or affinity labels for biochemical studies.
• Ligand Synthesis for Catalysis: Serves as a starting material for constructing N,S-bidentate ligands used in transition metal catalysis.
• Peptidomimetics & Drug Discovery: Incorporated into peptide backbones to modulate stability, bioavailability, and receptor interaction.

Basic Information

Product Name	2-[[(5-Methyl-1H-Imidazol-4-Yl)Methyl]Thio]Ethylamine Dihydrochloride
CAS No.	38603-72-4
Molecular Formula	C7H13N3S · 2HCl
Molecular Weight	272.19 g/mol
Synonyms	2-[(5-Methyl-1H-imidazol-4-yl)methylthio]ethylamine dihydrochloride; 2-((5-Methyl-1H-imidazol-4-yl)methylthio)ethanamine dihydrochloride; 4-[(2-Aminoethyl)thiomethyl]-5-methylimidazole dihydrochloride; 5-Methyl-4-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride; SKF 91488 dihydrochloride; Cimetidine intermediate analogue
EINECS	Contact for details

Quality Control

Our 2-[[(5-Methyl-1H-Imidazol-4-Yl)Methyl]Thio]Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.