Description

D-Glucose, o-(n-Acetyl-α-Neuraminosyl-(2→8))-o-(n-Acetyl-α-Neuraminosyl-(2→3))-o-β-D-Galactopyranosyl-(1→4)- is a complex, defined oligosaccharide derivative, specifically a trisialylated carbohydrate structure. This compound is of significant value as a high-purity biochemical standard and a critical intermediate for advanced glycobiology research and biopharmaceutical development. It is essential for researchers and manufacturers in the fields of vaccinology, therapeutic antibody characterization, and diagnostic assay development, where precise glycan structures are required to study cell signaling, pathogen recognition, and immune responses.

Application

• Glycobiology Research Standard: Used as a reference compound for the analysis and characterization of complex N-linked and O-linked glycans.
• Vaccine Adjuvant & Conjugate Development: Serves as a defined antigenic epitope or hapten in the synthesis of conjugate vaccines targeting bacterial pathogens like Neisseria meningitidis.
• Therapeutic Antibody Characterization: Critical for studying the glycosylation patterns of monoclonal antibodies (mAbs) to ensure consistency, efficacy, and safety.
• Diagnostic Reagent Synthesis: Employed in the production of detection probes and ELISA substrates for infectious disease and cancer biomarker assays.
• Enzyme Substrate & Inhibitor Studies: Acts as a specific substrate for sialyltransferases, neuraminidases (sialidases), and other glycosyl hydrolases.
• Cell Culture & Media Supplement: Used in specialized cell culture media to influence cellular glycosylation profiles in bioproduction.
• Drug Delivery System Research: Investigated for its potential in targeted drug delivery due to its specific receptor-binding properties.

Basic Information

Product Name	D-Glucose, o-(n-Acetyl-α-Neuraminosyl-(2→8))-o-(n-Acetyl-α-Neuraminosyl-(2→3))-o-β-D-Galactopyranosyl-(1→4)-
CAS No.	38598-36-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GD3 Trisaccharide; Disialylgalactosylglucose; Neu5Acα2-8Neu5Acα2-3Galβ1-4Glc; GD3 Oligosaccharide; Trisialyllactose derivative; Ganglioside GD3 core carbohydrate structure; (α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-D-Glc); Glycan standard (GD3)
EINECS	Contact for details

Quality Control

Our D-Glucose, o-(n-Acetyl-α-Neuraminosyl-(2→8))-o-(n-Acetyl-α-Neuraminosyl-(2→3))-o-β-D-Galactopyranosyl-(1→4)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure structural fidelity and purity, meeting the exacting standards required for life science research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.