Description

Z-L-Pyroglutamic Acid Dicyclohexylammonium Salt is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise chirality and stability in complex molecular construction. It serves as a key intermediate in the development of pharmaceuticals, peptides, and fine chemicals, making it indispensable for R&D and production teams in the life sciences and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those containing pyroglutamic acid motifs.
• Peptide Synthesis: Used as a protected glutamic acid derivative in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Bioconjugation & Linker Chemistry: Serves as a versatile spacer or linker molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chiral Building Block: Provides a source of defined stereochemistry for the asymmetric synthesis of natural products and bioactive compounds.
• Biochemical Research: Employed in enzymatic studies and as a standard or reagent in analytical and metabolic research.
• Fine Chemical Production: Acts as an intermediate in the manufacture of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	Z-L-Pyroglutamic Acid Dicyclohexylammonium Salt
CAS No.	38596-35-9
Molecular Formula	C24H36N2O5
Molecular Weight	432.56 g/mol
Synonyms	N-Carbobenzoxy-L-pyroglutamic Acid Dicyclohexylammonium Salt; Z-L-Pyroglutamic Acid DCHA Salt; N-Cbz-L-pyroglutamic Acid Dicyclohexylamine Salt; (S)-5-Oxo-1-((phenylmethoxy)carbonyl)pyrrolidine-2-carboxylic Acid Dicyclohexylammonium Salt; N-α-Carbobenzyloxy-L-pyroglutamic Acid Dicyclohexylammonium Salt; Z-L-Pyr-OH·DCHA; N-Cbz-L-Pyr-OH·DCHA; L-Pyroglutamic Acid, N-carbobenzoxy-, compd. with dicyclohexylamine (1:1)
EINECS	Contact for details

Quality Control

Our Z-L-Pyroglutamic Acid Dicyclohexylammonium Salt is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.