Description

8-Bromo-2,3-dihydroquinolin-4(1H)-one is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a functionalized quinolinone core that is crucial for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the creation of organic electronic materials, dyes, and photostable compounds due to its bromine substituent for further functionalization.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and ring-forming transformations.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects requiring specific, high-purity brominated heterocycles.

Basic Information

Product Name	8-Bromo-2,3-dihydroquinolin-4(1H)-one
CAS No.	38470-29-0
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	8-Bromo-1,2,3,4-tetrahydro-4-oxoquinoline; 8-Bromo-1,2,3,4-tetrahydroquinolin-4-one; 8-Bromo-3,4-dihydro-2H-quinolin-4-one; 8-Bromo-4-hydroxy-1,2,3,4-tetrahydroquinoline; 8-Bromocarbostyril; 8-Bromotetrahydro-4-quinolone; 4(1H)-Quinolinone, 8-bromo-2,3-dihydro-
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,3-dihydroquinolin-4(1H)-one is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity building blocks for research and cGMP-compliant development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.