Description

8-Fluoro-2,3-dihydroquinolin-4-one is a fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the fluorine atom and dihydroquinolinone core impart desirable biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance bioavailability and environmental persistence.
• Material Science: Used in the research of organic electronic materials and advanced polymers, where fluorinated quinolinone derivatives can influence electronic properties and material stability.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	8-Fluoro-2,3-dihydroquinolin-4-one
CAS No.	38470-28-9
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	8-Fluoro-1,2-dihydro-4(3H)-quinolinone; 8-Fluoro-3,4-dihydro-2H-quinolin-4-one; 8-Fluoro-2,3-dihydro-4(1H)-quinolinone; 8-Fluoro-1,2-dihydro-4-quinolone; 4(1H)-Quinolinone, 8-fluoro-2,3-dihydro-; 8-Fluoro-3,4-dihydro-2H-1-quinolinone; 8-Fluoro-2,3-dihydroquinolin-4(1H)-one
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2,3-dihydroquinolin-4-one is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.