Description

6-Fluoro-2,3-Dihydroquinolin-4(1H)-One is a high-value fluorinated heterocyclic building block, a key intermediate in modern synthetic organic chemistry. Its core value lies in its fused quinolinone structure, which provides a versatile scaffold for constructing more complex molecules, particularly in the pharmaceutical sector. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science: Acts as a building block for creating specialty chemicals, organic light-emitting diodes (OLEDs), and advanced polymers with unique electronic or photophysical properties.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) for library synthesis and structure-activity relationship (SAR) studies.
• Fluorine Chemistry: A valuable substrate for further fluorination or functionalization reactions, leveraging the existing fluorine atom for selective synthesis.

Basic Information

Product Name	6-Fluoro-2,3-Dihydroquinolin-4(1H)-One
CAS No.	38470-26-7
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	6-Fluoro-1,2,3,4-tetrahydro-4-oxoquinoline; 6-Fluoro-1,2,3,4-tetrahydroquinolin-4-one; 6-Fluoro-3,4-dihydro-2H-quinolin-4-one; 6-Fluoro-4-hydroxy-3,4-dihydro-2H-quinoline; 4(1H)-Quinolinone, 6-fluoro-2,3-dihydro-; 38470-26-7; 6-Fluoro-2,3-dihydro-1H-quinolin-4-one
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2,3-Dihydroquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP (Good Manufacturing Practice) and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.