Description

2'-(Bromomethyl)-[1,1'-Biphenyl]-2-Carboxylic Acid Methyl Ester is a versatile biphenyl-based organic intermediate featuring both a bromomethyl group and a methyl ester moiety. This compound is highly valued for its dual functional handles, which enable its use as a key building block in sophisticated multi-step organic syntheses. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with biphenyl or substituted biphenyl scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the biphenyl core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers requiring functionalized biphenyl units.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and library generation.

Basic Information

Product Name	2'-(Bromomethyl)-[1,1'-Biphenyl]-2-Carboxylic Acid Methyl Ester
CAS No.	38399-65-4
Molecular Formula	C16H15BrO2
Molecular Weight	319.20 g/mol
Synonyms	Methyl 2'-(Bromomethyl)biphenyl-2-carboxylate; 2'-(Bromomethyl)-2-biphenylcarboxylic Acid Methyl Ester; [1,1'-Biphenyl]-2-carboxylic Acid, 2'-(Bromomethyl)-, Methyl Ester; Methyl 2'-(Bromomethyl)[1,1'-biphenyl]-2-carboxylate; o-Tolyl 2-Bromomethylbenzoate Methyl Ether Derivative; Biphenyl-2-carboxylic Acid, 2'-(Bromomethyl)-, Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 2'-(Bromomethyl)-[1,1'-Biphenyl]-2-Carboxylic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profile. We support cGMP-compliant manufacturing for advanced projects upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.