Description

2-Biphenyl-2'-Iodo-Carboxylic Acid is a specialized iodinated biphenyl carboxylic acid derivative, serving as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid group and an iodine atom on the biphenyl scaffold, makes it a versatile building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and ligand synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and inflammatory pathways.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the biphenyl core for biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Negishi, and Stille couplings to form new carbon-carbon bonds.
• Ligand Synthesis: Utilized for preparing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A crucial reagent in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	2-Biphenyl-2'-Iodo-Carboxylic Acid
CAS No.	38399-49-4
Molecular Formula	C13H9IO2
Molecular Weight	324.12 g/mol
Synonyms	[1,1'-Biphenyl]-2-carboxylic acid, 2'-iodo-; 2'-Iodo[1,1'-biphenyl]-2-carboxylic acid; 2'-Iodobiphenyl-2-carboxylic Acid; 2-(2-Iodophenyl)benzoic Acid; o-Iodobiphenyl-2-carboxylic Acid; 2-Carboxy-2'-iodobiphenyl; NSC 403108
EINECS	Contact for details

Quality Control

Our 2-Biphenyl-2'-Iodo-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.