Description

1-Bromo-2-Cyclopropoxybenzene is a versatile aryl bromide building block featuring a cyclopropoxy substituent. This compound matters for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a substituted benzene core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromine atom serves as a handle for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as hole-transport or emissive layers, due to its aromatic structure.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	1-Bromo-2-Cyclopropoxybenzene
CAS No.	38380-86-8
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	2-Bromophenyl cyclopropyl ether; o-Bromophenyl cyclopropyl ether; 1-Bromo-2-(cyclopropyloxy)benzene; Cyclopropyl 2-bromophenyl ether; Benzene, 1-bromo-2-cyclopropoxy-; 2-Cyclopropoxy-1-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Cyclopropoxybenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.