Description

L-Cystine Bis(T-Butyl Ester) Dihydrochloride is a protected derivative of the essential amino acid L-cystine, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is crucial for researchers and manufacturers requiring precise control over disulfide bond formation and side-chain protection during complex molecular assembly. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for applications ranging from novel drug development to the production of specialized biochemical reagents.

Application

• Peptide Synthesis Intermediate: A key building block in solid-phase and solution-phase peptide synthesis, particularly for introducing protected cystine residues.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based therapeutics, including hormones, enzyme inhibitors, and targeted drug candidates.
• Bioconjugation Chemistry: Serves as a precursor for creating cross-linking agents or modifying biomolecules to study protein interactions or create drug conjugates.
• Production of Biochemical Reagents: Employed in the manufacture of specialized reagents, substrates, and standards for diagnostic and research applications.
• Academic & Industrial Research: A valuable tool in chemical biology and medicinal chemistry labs for studying disulfide bridge formation and stability.

Basic Information

Product Name	L-Cystine Bis(T-Butyl Ester) Dihydrochloride
CAS No.	38261-78-8
Molecular Formula	C16H32N2O4S2 · 2HCl
Molecular Weight	453.48 g/mol
Synonyms	L-Cystine di-tert-butyl ester dihydrochloride; H-Cys(Trt)-OtBu·HCl; (R,R)-2,2'-Disulfanediylbis(2-amino-3-(tert-butoxy)-3-oxopropanoic acid) dihydrochloride; N,N'-Bis(tert-butoxycarbonyl)-L-cystine dihydrochloride; Boc-Cys(Trt)-OtBu·HCl; L-Cystine, bis(1,1-dimethylethyl) ester, dihydrochloride; tert-Butyl L-cystinate dihydrochloride
EINECS	Contact for details

Quality Control

Our L-Cystine Bis(T-Butyl Ester) Dihydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing specific results for purity, optical rotation, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.