Description

Diethyl 4-Bromobenzyl Phosphonate is a high-purity organophosphorus compound serving as a versatile synthetic intermediate. Its primary value lies in enabling the efficient construction of complex molecules through key carbon-carbon and carbon-phosphorus bond-forming reactions. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable building block for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing benzylphosphonate or aryl bromide motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing phosphonate-based ligands for metal catalysis and organocatalysts.
• Material Science Research: Employed in the creation of flame retardants, plasticizers, and specialty polymers.
• Horner-Wadsworth-Emmons (HWE) Reaction: A crucial reagent for the stereoselective synthesis of alkenes, widely used in fine chemical production.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed couplings, such as the Suzuki-Miyaura reaction, after appropriate functional group transformation.

Basic Information

Product Name	Diethyl 4-Bromobenzyl Phosphonate
CAS No.	38186-51-5
Molecular Formula	C11H16BrO3P
Molecular Weight	307.12 g/mol
Synonyms	Diethyl (4-Bromobenzyl)phosphonate; (4-Bromobenzyl)phosphonic Acid Diethyl Ester; Phosphonic Acid, P-[(4-Bromophenyl)methyl]-, Diethyl Ester; Diethyl (p-Bromobenzyl)phosphonate; 4-Bromobenzylphosphonic Acid Diethyl Ester; Diethyl 4-Bromobenzylphosphonate; (p-Bromobenzyl)phosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 4-Bromobenzyl Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.