Description

4-Chloro-2-Isopropyl-Quinazoline is a versatile and high-value heterocyclic building block, primarily utilized in advanced organic synthesis. Its core value lies in its functionalized quinazoline scaffold, which serves as a critical intermediate for constructing more complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing novel active ingredients, particularly in the fields of oncology, CNS disorders, and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology: Used in the design and synthesis of molecular probes and tool compounds for studying biological pathways and target validation.
• Material Science: Potential intermediate for creating specialty chemicals, dyes, or functional materials with specific electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for methodological development and novel heterocyclic chemistry exploration.

Basic Information

Product Name	4-Chloro-2-Isopropyl-Quinazoline
CAS No.	38154-42-6
Molecular Formula	C₁₁H₁₁ClN₂
Molecular Weight	206.67 g/mol
Synonyms	4-Chloro-2-(propan-2-yl)quinazoline; 2-Isopropyl-4-chloroquinazoline; Quinazoline, 4-chloro-2-(1-methylethyl)-; 4-Chloro-2-(1-methylethyl)quinazoline; 38154-42-6; 4-Chloro-2-isopropyl-quinazoline; 2-(1-Methylethyl)-4-chloroquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Isopropyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.