Description

(20α)-3,16,17-Tridehydro-10,11-Dimethoxy-16-(Methoxycarbonyl)-19α-Methyl-18-Oxayohimban-4-Ium is a complex, synthetically derived indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chemical intermediate and reference standard for the development of novel bioactive molecules targeting neurological and cardiovascular systems. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and alkaloid research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex therapeutic agents, particularly those with indole alkaloid backbones.
• Medicinal Chemistry Research: Used as a key scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in HPLC, LC-MS, and NMR analysis.
• Biochemical Research: Investigated for its potential interactions with various biological receptors and enzymes due to its structural similarity to bioactive yohimbine analogs.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for the production of specialized fine chemicals.
• Academic Studies: A subject compound for advanced organic chemistry research focusing on alkaloid synthesis, stereochemistry, and reaction mechanisms.

Basic Information

Item	Details
Product Name	(20α)-3,16,17-Tridehydro-10,11-Dimethoxy-16-(Methoxycarbonyl)-19α-Methyl-18-Oxayohimban-4-Ium
CAS No.	38146-72-4
Molecular Formula	C23H26N2O5+
Molecular Weight	410.47 g/mol
Synonyms	16-Carbomethoxy-19α-methyl-18-oxayohimban-4-ium; 10,11-Dimethoxy-16-(methoxycarbonyl)-19α-methyl-18-oxayohimban-4-ium; Methyl 10,11-dimethoxy-19α-methyl-18-oxayohimban-16-carboxylate (cation); Yohimbine analog derivative; 18-Oxayohimbanium derivative; 19α-Methyl-18-oxayohimban-4-ium salt; 3,16,17-Tridehydroyohimban derivative
EINECS	Contact for details

Quality Control

Our (20α)-3,16,17-Tridehydro-10,11-Dimethoxy-16-(Methoxycarbonyl)-19α-Methyl-18-Oxayohimban-4-Ium is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and MS are provided and can be tailored to meet specific client or pharmacopeial requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.