Description

7-Hydroxybenzo(A)Pyrene is a key hydroxylated derivative of the polycyclic aromatic hydrocarbon benzo(a)pyrene. This compound is of significant interest in environmental and toxicological research as a primary metabolite and biomarker of exposure to its parent carcinogen. It is essential for laboratories and industries focused on analytical standards, metabolic pathway studies, and the development of detection methods for environmental pollutants and biological monitoring.

Application

• Analytical Reference Standard: Used as a certified standard in HPLC, GC-MS, and LC-MS for the quantification of benzo(a)pyrene metabolites in environmental and biological samples.
• Toxicology & Metabolic Studies: Critical for researching the metabolic activation, detoxification pathways, and DNA adduct formation of benzo(a)pyrene in vitro and in vivo.
• Environmental Monitoring: Employed in the calibration of equipment and validation of methods for detecting PAH (Polycyclic Aromatic Hydrocarbon) pollution in soil, water, and air particulates.
• Biomarker Research: Serves as a precise standard in developing immunoassays or other bioanalytical techniques for human biomonitoring and occupational health studies.
• Pharmaceutical Research: Used in studies investigating the mechanisms of chemical carcinogenesis and for screening potential chemopreventive agents.
• Quality Control & Method Development: Essential for laboratories in chemical, environmental, and contract research organizations (CROs) to develop, validate, and ensure the accuracy of analytical methods.

Basic Information

Product Name	7-Hydroxybenzo(A)Pyrene
CAS No.	37994-82-4
Molecular Formula	C₂₀H₁₂O
Molecular Weight	268.31 g/mol
Synonyms	7-Hydroxybenzo[a]pyrene; 7-OH-BaP; Benzo[a]pyren-7-ol; 7-Hydroxy-3,4-benzpyrene; 1-Hydroxybenzo[a]pyrene (positional isomer); 7-HBP; BaP-7-ol
EINECS	Contact for details

Quality Control

Our 7-Hydroxybenzo(A)Pyrene is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analysis using advanced techniques like HPLC and mass spectrometry to ensure high purity and precise identification. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency, meeting the rigorous demands of research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystals
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility Test	Conforms (typically in DMSO, methanol)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.