Description

1-[2-[2-(Carbamimidoyl-Ethyl-Amino)Ethyldisulfanyl]Ethyl]-1-Ethyl-Guanidine Dihydrobromide is a high-purity, disulfide-linked guanidine derivative primarily used as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel therapeutic agents and research tools. It is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on medicinal chemistry, peptide mimetics, and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring disulfide bridges for structural stability or targeted activity.
• Bioconjugation Reagent: Used for linking biomolecules (e.g., peptides, proteins, antibodies) to other entities via its reactive disulfide and guanidine groups.
• Medicinal Chemistry Research: Serves as a versatile scaffold for exploring structure-activity relationships (SAR) in drug discovery programs.
• Peptide Mimetic Development: Integral in creating peptidomimetics where the disulfide linkage and guanidine moiety mimic natural peptide structures for enhanced metabolic stability.
• Cross-linking Agent: Employed in material science and polymer chemistry to introduce reversible cross-links via disulfide bond formation.
• Biochemical Probe Synthesis: Used to create labeled probes for studying biological processes involving thiol-disulfide exchange.

Basic Information

Product Name	1-[2-[2-(Carbamimidoyl-Ethyl-Amino)Ethyldisulfanyl]Ethyl]-1-Ethyl-Guanidine Dihydrobromide
CAS No.	37914-87-7
Molecular Formula	C₁₀H₂₆Br₂N₆S₂
Molecular Weight	478.29 g/mol
Synonyms	1,1'-[Dithiobis(ethane-2,1-diylnitrilo(ethane-2,1-diyl))]bis(3-ethylguanidine) Dihydrobromide; N,N'-Bis[2-[[2-(3-ethylguanidino)ethyl]dithio]ethyl]-1,1-dimethyl-2-imino-1,2-ethanediamine Dihydrobromide; 3-Ethyl-1-[2-[[2-[(3-ethylguanidino)ethyl]dithio]ethyl]guanidine Dihydrobromide; Guanidine, N,N'-[dithiobis(ethylenenitriloethylidyne)]bis[N-ethyl-], dihydrobromide; Bisthioethyl Ethyl Guanidine Dihydrobromide; Disulfide-linked Ethyl Guanidine Dihydrobromide; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1-[2-[2-(Carbamimidoyl-Ethyl-Amino)Ethyldisulfanyl]Ethyl]-1-Ethyl-Guanidine Dihydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with pharmaceutical intermediate standards. Certificates of Analysis (COA) with complete chromatographic data and specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent oxidation of the disulfide bond.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	97.0 - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.