Description

2-Aminooxyethylamine Dihydrochloride is a versatile bifunctional building block containing both an aminooxy and a primary amine group, each protected as a hydrochloride salt. This compound is critical for researchers and manufacturers requiring high-purity, reactive intermediates for advanced synthesis. It is particularly valuable for professionals in pharmaceutical development, bioconjugation, and materials science who need reliable, consistent quality for sensitive chemical transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly for conjugation and linker chemistry.
• Bioconjugation Reagent: Used for site-specific labeling and crosslinking of proteins, antibodies, and oligonucleotides via its reactive aminooxy group.
• Chemical Biology Probe Synthesis: Essential for creating affinity probes, activity-based probes, and other tools for studying biological systems.
• Polymer & Materials Science: Serves as a monomer or crosslinker in the development of functional polymers, hydrogels, and smart materials.
• Peptide Synthesis & Modification: Enables the introduction of aminooxy functionality into peptide chains for further derivatization or cyclization.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	2-Aminooxyethylamine Dihydrochloride
CAS No.	37866-45-8
Molecular Formula	C2H9N2O·2HCl
Molecular Weight	157.03 g/mol
Synonyms	O-(2-Aminoethyl)hydroxylamine Dihydrochloride; 2-(Aminooxy)ethanamine Dihydrochloride; Aminooxyethylamine Dihydrochloride; N-(2-Aminooxyethyl)amine Dihydrochloride; AOA Dihydrochloride; Hydroxylamine, O-(2-aminoethyl)-, Dihydrochloride; 1-Amino-2-(aminooxy)ethane Dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aminooxyethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.