Description

5-Azatricyclo[4.1.0.02,4]Heptane-5-Carboxylicacid,Methylester is a specialized bicyclic organic compound featuring a strained aziridine ring fused to a cyclopropane moiety, making it a valuable and structurally unique building block in advanced synthetic chemistry. Its rigid, three-dimensional scaffold is prized for introducing significant molecular complexity and specific stereoelectronic properties into target molecules. This high-purity intermediate is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring constrained peptide mimetics.
• Agrochemical Synthesis: Serves as a precursor for creating new herbicides, fungicides, or insecticides with unique modes of action due to its strained ring system.
• Methodology Development: Used in academic and industrial research to develop new synthetic methodologies involving strained heterocycles and cyclopropanation reactions.
• Ligand and Catalyst Design: Employed in the construction of sophisticated chiral ligands or organocatalysts that leverage its three-dimensional geometry.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with novel thermal or mechanical properties.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function or protein-protein interactions due to its ability to mimic transition states or rigidify structures.

Basic Information

Product Name	5-Azatricyclo[4.1.0.02,4]Heptane-5-Carboxylicacid,Methylester
CAS No.	37835-31-7
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	Methyl 5-azatricyclo[4.1.0.0²,⁴]heptane-5-carboxylate; 5-Carbomethoxy-5-azatricyclo[4.1.0.0²,⁴]heptane; 1-Azabicyclo[4.1.0]heptane-1-carboxylic acid, methyl ester; Methyl 1-azabicyclo[4.1.0]heptane-1-carboxylate; 5-Azatricyclo[4.1.0.0²,⁴]heptane-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Azatricyclo[4.1.0.02,4]Heptane-5-Carboxylicacid,Methylester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.