Description

S-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene is a high-value, chiral binaphthyl derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile precursor to chiral ligands and catalysts, enabling the production of enantiomerically pure pharmaceuticals and specialty chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for asymmetric synthesis.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of axially chiral phosphines, diamines, and other privileged ligand frameworks used in asymmetric catalysis.
• Pharmaceutical Intermediates: Employed in the synthesis of active pharmaceutical ingredients (APIs) where stereochemical control is paramount.
• Advanced Material Development: Used in the creation of chiral polymers, liquid crystals, and molecular recognition systems for sensor technology.
• Agrochemical Research: Serves as a building block for developing enantioselective pesticides and herbicides.
• Catalyst Development: Integral for constructing novel organocatalysts and transition metal complexes for industrial-scale asymmetric transformations.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	S-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene
CAS No.	37803-02-4
Molecular Formula	C22H16Br2
Molecular Weight	440.17 g/mol
Synonyms	(S)-2,2'-Bis(bromomethyl)-1,1'-binaphthalene; (S)-2,2'-Bis(bromomethyl)-1,1'-binaphthyl; (S)-BINOL-Br; (S)-1,1'-Bi-2-naphthol, 2,2'-bis(bromomethyl)-; (S)-2,2'-Dibromomethyl-1,1'-binaphthalene; (S)-BINOL-DiBr; (S)-BINOL-(CH2Br)2; (S)-2,2'-Bis(bromomethyl)[1,1'-binaphthalene]-2,2'-diyl
EINECS	Contact for details

Quality Control

Our S-2,2'-Bis(Bromomethyl)-1,1'-Binaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.