Description

(1S,2R,3R,8S)-4-Bromocubane-1-Carboxylic Acid is a highly specialized and synthetically valuable derivative of the cubane scaffold, prized for its unique three-dimensional geometry and functional handles for further chemical elaboration. This compound matters as a critical building block in advanced materials science and pharmaceutical research, where its strained hydrocarbon framework can impart novel properties to target molecules. It is primarily needed by R&D chemists and process development scientists in the fields of medicinal chemistry, high-energy materials, and supramolecular engineering.

Application

• Medicinal Chemistry Intermediate: Serves as a rigid, three-dimensional core structure for designing novel drug candidates with improved metabolic stability and binding affinity.
• High-Energy Materials Research: Used in the development of novel propellants and explosives due to the high strain energy and density of the cubane cage.
• Advanced Polymer & Material Science: Acts as a monomer or cross-linking agent to create polymers with unique thermal and mechanical properties.
• Organic Synthesis Building Block: Provides a versatile platform for further functionalization via the carboxylic acid and bromo substituents for creating complex molecular architectures.
• Academic & Industrial R&D: Employed in fundamental research to study strain-release chemistry and structure-property relationships.

Basic Information

Product Name	(1S,2R,3R,8S)-4-Bromocubane-1-Carboxylic Acid
CAS No.	37794-29-9
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	4-Bromocubane-1-carboxylic acid; (1S,2R,3R,8S)-4-Bromopentacyclo[4.2.0.02,5.03,8.04,7]octane-1-carboxylic acid; 4-Bromo-1-cubanecarboxylic acid; Bromocubanecarboxylic acid; Cubane-1-carboxylic acid, 4-bromo derivative
EINECS	Contact for details

Quality Control

Our (1S,2R,3R,8S)-4-Bromocubane-1-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.