Description

3-Chloro-2-(Chloromethyl)-4-Methylquinoline Hydrochloride is a versatile and high-purity quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionalization, making it an essential intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), specialty chemicals, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Synthesis: Building block for developing novel pesticides, herbicides, and fungicides with enhanced efficacy.
• Organic Synthesis Reagent: Used in heterocyclic chemistry for constructing complex fused-ring systems and functionalized quinolines.
• Material Science Research: Intermediate in the development of organic semiconductors, ligands for catalysts, and fluorescent dyes.
• Chemical Research & Development: Serves as a standard or starting material in method development and scale-up studies for fine chemical production.

Basic Information

Product Name	3-Chloro-2-(Chloromethyl)-4-Methylquinoline Hydrochloride
CAS No.	37781-33-2
Molecular Formula	C12H12Cl2N·HCl
Molecular Weight	278.60 g/mol (Free base: 242.14 g/mol)
Synonyms	2-(Chloromethyl)-3-chloro-4-methylquinoline Hydrochloride; 4-Methyl-3-chloro-2-chloromethylquinoline Hydrochloride; 3-Chloro-2-chloromethyl-4-methylquinoline HCl; Quinoline, 3-chloro-2-(chloromethyl)-4-methyl-, hydrochloride; 37781-33-2; 3-Chloro-2-(chloromethyl)-4-methylquinoline monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Chloromethyl)-4-Methylquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.