Description

Spiro[3H-2-Benzopyran-3,4'-Piperidin]-1(4H)-One is a complex spirocyclic organic compound featuring a benzopyran moiety fused to a piperidine ring. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate (API) and a versatile scaffold in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries. The compound's spirocyclic structure is of significant interest for developing novel bioactive molecules targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in drug discovery programs to explore new chemical space.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Synthesis: Employed in organic synthesis for constructing complex, three-dimensional molecular architectures due to its spirocyclic core.
• Academic Research: Utilized in university and institutional labs for studying spirocyclic compound properties and reaction mechanisms.

Basic Information

Product Name	Spiro[3H-2-Benzopyran-3,4'-Piperidin]-1(4H)-One
CAS No.	37751-73-8
Molecular Formula	C₁₄H₁₅NO₂
Molecular Weight	229.28 g/mol
Synonyms	1',4'-Dihydrospiro[2-benzopyran-3,4'-piperidin]-1-one; Spiro[2-benzopyran-3,4'-piperidine]-1(4H)-one; 1,4-Dihydrospiro[2-benzopyran-3,4'-piperidin]-1-one; 37751-73-8; Spiro(benzopyran-3,4'-piperidin)-1-one; Spiro[3H-2,1-benzoxathiole-3,4'-piperidine] 1,1-dioxide (related structure); Spirocyclic benzopyran-piperidinone
EINECS	Contact for details

Quality Control

Our Spiro[3H-2-Benzopyran-3,4'-Piperidin]-1(4H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.