Description

5-Methylenespiro[2.4]heptane is a specialized spirocyclic hydrocarbon building block with the CAS registry number 37745-07-6. This compound is valued for its unique strained ring structure, which makes it a versatile intermediate in advanced organic synthesis and materials science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating spirocyclic scaffolds with potential biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where its unique carbon skeleton can impart specific activity profiles.
• Advanced Material Synthesis: Acts as a monomer or cross-linking agent in the production of specialty polymers and high-performance resins with tailored thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, ring-opening polymerizations, and the construction of complex natural product analogs.
• Ligand and Catalyst Development: Utilized as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing unique musk or woody odorant molecules due to its bicyclic framework.

Basic Information

Product Name	5-Methylenespiro[2.4]heptane
CAS No.	37745-07-6
Molecular Formula	C8H12
Molecular Weight	108.18 g/mol
Synonyms	Spiro[2.4]hept-5-ene, 5-Methylene-; 5-Methylenespiro[2.4]heptane; 5-Methylidene-1,6-dihydrospiro[2.4]heptane; 37745-07-6; Spiro[2.4]hepta-5,6-diene (incorrect but common); 5-Methylenespiro(2.4)heptane; 5-Methylenespiro[2,4]heptane
EINECS	Contact for details

Quality Control

Our 5-Methylenespiro[2.4]heptane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, GC-MS, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical parameters. Our quality system is designed to meet the stringent requirements of research and development applications, ensuring reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term stability, storage under an inert atmosphere (e.g., nitrogen or argon) in a freezer (-20°C) is recommended to prevent potential polymerization or degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.