Description

5-(4-Fluorobenzoyl)-6-Methyl-5H-1,3-Dioxolo[4,5-F]Indole-7-Acetic Acid is a high-purity, synthetically derived indole acetic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular architecture, which is essential for constructing complex active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly within the fields of oncology and neurology.

Application

This specialized intermediate is engineered for high-value synthesis applications, primarily within the life sciences sector.

• Pharmaceutical Intermediate: Key building block in the synthesis of novel, potent drug candidates.
• Oncology Research: Used in the development of targeted cancer therapies and investigational new drugs.
• Neurological Drug Development: Serves as a precursor in the synthesis of compounds targeting central nervous system disorders.
• Chemical Biology & Proteomics: Utilized as a molecular probe or scaffold for studying biological pathways and protein interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for medicinal chemistry projects and novel heterocyclic compound synthesis.

Basic Information

Item	Details
Product Name	5-(4-Fluorobenzoyl)-6-Methyl-5H-1,3-Dioxolo[4,5-F]Indole-7-Acetic Acid
CAS No.	37585-58-3
Molecular Formula	C19H14FNO5
Molecular Weight	355.32 g/mol
Synonyms	5-(4-Fluorobenzoyl)-6-methyl-1,3-dioxolo[4,5-f]indole-7-acetic acid; 6-Methyl-5-(4-fluorobenzoyl)-5H-[1,3]dioxolo[4,5-f]indole-7-acetic acid; 5H-1,3-Dioxolo[4,5-f]indole-7-acetic acid, 5-(4-fluorobenzoyl)-6-methyl-; (7-Carboxymethyl-6-methyl-5H-[1,3]dioxolo[4,5-f]indol-5-yl)-(4-fluorophenyl)methanone; Fluorobenzoyl methyl dioxoloindole acetic acid; 37585-58-3; FB-MDIA
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluorobenzoyl)-6-Methyl-5H-1,3-Dioxolo[4,5-F]Indole-7-Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and development work. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and the absence of specified impurities. Certificates of Analysis (COA) detailing all test results are provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.