Description

4-Hydroxybenzo[A]Pyrene is a hydroxylated derivative of the well-studied polycyclic aromatic hydrocarbon, benzo[a]pyrene. This compound is of significant interest in research and analytical chemistry, particularly for its role as a metabolite and biomarker of exposure to its parent compound. It is primarily utilized by research institutions, environmental testing laboratories, and pharmaceutical development teams for toxicological studies, metabolic pathway analysis, and as a reference standard in analytical methods.

Application

• Analytical Reference Standard: Used for the calibration and validation of analytical instruments (e.g., HPLC, GC-MS) in environmental and biological monitoring.
• Toxicology and Metabolic Research: Serves as a key metabolite in studies investigating the biotransformation, DNA adduct formation, and carcinogenic mechanisms of benzo[a]pyrene.
• Environmental Analysis: Employed as a standard for detecting and quantifying hydroxylated PAH metabolites in soil, water, and air pollution studies.
• Biomarker Development: Used in the development of assays to measure human exposure to PAHs through the analysis of urinary or blood metabolites.
• Pharmaceutical Research: Applied in studies exploring drug metabolism interactions and enzyme (e.g., CYP450) activity related to PAH processing.
• Chemical Synthesis Intermediate: Can serve as a building block or precursor for the synthesis of more complex molecules for specialized research applications.

Basic Information

Product Name	4-Hydroxybenzo[A]Pyrene
CAS No.	37574-48-4
Molecular Formula	C₂₀H₁₂O
Molecular Weight	268.31 g/mol
Synonyms	4-Hydroxybenzo[a]pyrene; 4-Hydroxy-BaP; Benzo[a]pyren-4-ol; 4-HBP; 4-OH-BaP; 4-Hydroxy-3,4-benzpyrene; Hydroxybenzo(a)pyrene
EINECS	Contact for details

Quality Control

Our 4-Hydroxybenzo[A]Pyrene is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), identity confirmation (by IR/UV), and related substance profiles are provided and available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystals
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0% (Research Grade)
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Loss on Drying	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.