Description

n-Acetylneuraminyl-Lactose, also known as Neuramin-Lactose, is a specific sialylated lactose derivative that serves as a crucial biochemical tool and reference standard. This compound, comprising α-Neunac-(2-3)- and -(2-6)-β-D-Gal-(1-4)-D-Glc isomers, is essential for studying carbohydrate-protein interactions, particularly those involving sialic acid. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic industries for applications in glycobiology, vaccine research, and the synthesis of complex oligosaccharides.

Application

• Glycobiology Research: Used as a critical substrate and standard for studying sialidase (neuraminidase) enzyme activity, specificity, and inhibition.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the research and development of antiviral agents, especially influenza neuraminidase inhibitors.
• Diagnostic Reagents: Employed in the formulation and calibration of diagnostic kits for detecting viral infections or specific carbohydrate-binding proteins.
• Biochemical Synthesis: Acts as a building block or precursor for the enzymatic or chemical synthesis of more complex gangliosides and glycoconjugates.
• Cell Biology Studies: Utilized to investigate cell surface recognition processes, signal transduction, and the role of sialylated glycans in cell adhesion and communication.
• Quality Control Standard: Provides a high-purity reference material for the quality assurance of related biopharmaceuticals and diagnostic products.

Basic Information

Product Name	n-Acetylneuraminyl-Lactose
CAS No.	37449-93-7
Molecular Formula	C23H39NO19
Molecular Weight	633.56 g/mol
Synonyms	Neuramin-Lactose; 3'-Sialyllactose (mixed isomers); α-N-Acetylneuraminyl-(2→3/6)-β-D-galactopyranosyl-(1→4)-D-glucopyranose; Sialyllactose; N-Acetylneuraminosyllactose; Lactosylneuraminic acid; NANA-Lac; 37449-93-7
EINECS	Contact for details

Quality Control

Our n-Acetylneuraminyl-Lactose is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer ratio, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place, ideally at 2-8°C under desiccated conditions for long-term stability. For laboratory use, allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Isomer Ratio (α2-3 / α2-6)	Specified on COA
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.