Description

3-Hydroxyphthalic Anhydride is a versatile aromatic anhydride derivative characterized by a reactive anhydride group and a phenolic hydroxyl group. This bifunctional structure makes it a valuable key intermediate for synthesizing complex molecules, particularly in advanced material and pharmaceutical chemistry. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and polymer industries for constructing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), especially those with complex polycyclic or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent for epoxy resins, polyimides, and other high-performance polymers, enhancing thermal and mechanical properties.
• Dye & Pigment Manufacturing: Acts as a precursor for the synthesis of specialized organic dyes and pigments.
• Fluorescent Probe Synthesis: Utilized in research to create fluorescent markers and sensors for biological and chemical detection.
• Corrosion Inhibitor Formulation: Incorporated into coatings and additives for metal surface protection.
• Academic & Industrial Research: A valuable reagent for organic synthesis and material science research in laboratory settings.

Basic Information

Item	Detail
Product Name	3-Hydroxyphthalic Anhydride
CAS No.	37418-88-5
Molecular Formula	C8H4O4
Molecular Weight	164.12 g/mol
Synonyms	3-Hydroxyisobenzofuran-1,3-dione; 3-Hydroxy-1,3-dihydroisobenzofuran-1-one; 3-Hydroxyphthalic acid cyclic anhydride; 1,3-Dihydro-3-hydroxy-1-oxoisobenzofuran; 3-Hydroxyphthalic acid anhydride; 3-Hydroxy-1-oxo-1H-isobenzofuran; 3-Carboxyphthalic anhydride (tautomeric form)
EINECS	Contact for details

Quality Control

Our 3-Hydroxyphthalic Anhydride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR spectroscopy, to ensure it meets high-purity standards suitable for sensitive synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.