Description

(2R,3R)-(+)-2,3-Epoxy-3-(4-Nitrophenyl)-1-Propanol is a high-purity chiral epoxide building block of significant interest in advanced organic synthesis. Its defined stereochemistry and reactive oxirane ring make it a critical intermediate for constructing complex, optically active molecules. This compound is primarily needed by pharmaceutical research and fine chemical manufacturers developing new active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in therapeutic areas requiring specific stereochemistry.
• Asymmetric Synthesis: Used in the preparation of chiral ligands, catalysts, and auxiliaries for stereoselective chemical transformations.
• Agrochemical Research: Serves as a building block for developing novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique optical or mechanical properties.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, particularly in epoxide ring-opening reactions and cascade syntheses.

Basic Information

Item	Details
Product Name	(2R,3R)-(+)-2,3-Epoxy-3-(4-Nitrophenyl)-1-Propanol
CAS No.	37141-32-5
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	(2R,3R)-2,3-Epoxy-3-(4-nitrophenyl)propan-1-ol; (+)-trans-2,3-Epoxy-3-(4-nitrophenyl)-1-propanol; (2R,3R)-(-)-2,3-Epoxy-3-(p-nitrophenyl)-1-propanol (enantiomer); 4-Nitro-trans-β-methylglycidol; (2R,3R)-3-(4-Nitrophenyl)oxiranemethanol; p-Nitrophenyl glycidol; (R,R)-(-)-p-Nitrophenylglycidol; A chiral nitroaryl epoxide.
EINECS	Contact for details

Quality Control

Our (2R,3R)-(+)-2,3-Epoxy-3-(4-Nitrophenyl)-1-Propanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high enantiomeric purity and chemical identity, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) detailing chiral purity (HPLC), assay, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.