Description

α-D-Ribofuranose,1,2-o-(1-Methylethylidene)- is a protected ribose derivative, a crucial building block in organic synthesis and pharmaceutical manufacturing. This compound is valued for its role in creating nucleoside analogs and other complex molecules where the selective protection of the ribose sugar is required. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Nucleoside and Nucleotide Synthesis: A key intermediate in the production of modified nucleosides, which are essential for antiviral and anticancer drug development.
• Pharmaceutical Intermediates: Serves as a protected sugar moiety in the synthesis of complex carbohydrate-based APIs and prodrugs.
• Biochemical Research: Used as a precursor in enzymatic studies and for the preparation of labeled compounds for metabolic pathway analysis.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific sugar chemistry.
• Glycochemistry: Acts as a starting material for the synthesis of glycosides and other glycoconjugates with biological activity.

Basic Information

Product Name	α-D-Ribofuranose,1,2-o-(1-Methylethylidene)-
CAS No.	37077-81-9
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	1,2-O-Isopropylidene-α-D-ribofuranose; 1,2-O-(1-Methylethylidene)-α-D-ribofuranose; α-D-Ribofuranose, 1,2-O-(1-methylethylidene)-; Isopropylidene Ribose; 1,2-O-Isopropylidene-α-D-ribofuranose; 1,2-O-(1-Methylethylidene)-α-D-ribofuranose; Protected D-Ribose; 1,2-Acetonide of D-ribose
EINECS	253-347-5

Quality Control

Our α-D-Ribofuranose,1,2-o-(1-Methylethylidene)- is produced under strict quality management systems. We offer material suitable for research and industrial synthesis, with typical purity levels meeting the requirements for advanced chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.