Description

4-Chloro-3-Methylacetophenone is a versatile chlorinated aromatic ketone that serves as a critical building block in advanced organic synthesis. Its molecular structure makes it a valuable intermediate for the development of pharmaceuticals, agrochemicals, and functional materials. This compound is particularly sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with chlorinated aryl ketone backbones.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, leveraging the reactivity of the chloro and acetyl groups.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, nucleophilic substitution, and reduction reactions to create more complex molecules.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic processes.
• Material Science Research: Investigated for the preparation of monomers or additives for specialty polymers and advanced materials.
• Dye and Pigment Intermediate: Utilized in the production of certain dyes and organic pigments due to its aromatic structure.

Basic Information

Product Name	4-Chloro-3-Methylacetophenone
CAS No.	37074-39-8
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	1-(4-Chloro-3-methylphenyl)ethanone; 4'-Chloro-3'-methylacetophenone; 3-Methyl-4-chloroacetophenone; p-Chloro-m-methylacetophenone; 4-Chloro-3-methylacetophenone; 4-Chloro-3'-methylacetophenone; Ethanone, 1-(4-chloro-3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methylacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.