Description

1,2,3,4-Tetrahydro-1-Oxo-4Ah-Benzo[C]Quinolizine-4A-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex organic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Organic Synthesis Building Block: Used in the construction of complex nitrogen-containing heterocycles, which are prevalent in many agrochemicals and dyes.
• Academic & R&D Laboratories: Employed in methodological development and as a reference standard in chemical research.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high-purity, structurally defined intermediates.

Basic Information

Product Name	1,2,3,4-Tetrahydro-1-Oxo-4Ah-Benzo[C]Quinolizine-4A-Carbonitrile
CAS No.	37045-09-3
Molecular Formula	C₁₄H₁₂N₂O
Molecular Weight	224.26 g/mol
Synonyms	1,2,3,4-Tetrahydro-1-oxo-4aH-benzo[c]quinolizine-4a-carbonitrile; 4a-Cyano-1,2,3,4-tetrahydro-1-oxobenzo[c]quinolizine; Benzo[c]quinolizine-4a-carbonitrile, 1,2,3,4-tetrahydro-1-oxo-; 4aH-Benzo[c]quinolizine-4a-carbonitrile, 1,2,3,4-tetrahydro-1-oxo-; 37045-09-3; Tetrahydrooxobenzoquinolizinecarbonitrile
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-1-Oxo-4Ah-Benzo[C]Quinolizine-4A-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.