Description

Benzo[H]Quinoline-3-Carboxylic Acid, 4-Chloro-, Ethyl Ester is a specialized heterocyclic organic compound that serves as a high-value synthetic intermediate. Its precise molecular architecture makes it a critical building block for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and advanced organic electronics sectors seeking to introduce complex quinoline-based frameworks into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated quinoline structure.
• Material Science Research: Serves as a monomer or dopant in the development of organic semiconductors, light-emitting diodes (OLEDs), and other functional organic materials.
• Dye & Pigment Industry: Acts as a starting material for synthesizing complex heterocyclic dyes and fluorescent markers.
• Catalyst Ligand Preparation: Utilized to create sophisticated nitrogen-containing ligands for transition metal catalysis in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for methodological studies and building block chemistry in university and CRO laboratories.

Basic Information

Product Name	Benzo[H]Quinoline-3-Carboxylic Acid, 4-Chloro-, Ethyl Ester
CAS No.	37041-30-8
Molecular Formula	C₁₆H₁₂ClNO₂
Molecular Weight	285.73 g/mol
Synonyms	4-Chloro-benzo[h]quinoline-3-carboxylic acid ethyl ester; Ethyl 4-chlorobenzo[h]quinoline-3-carboxylate; 4-Chloro-1-azanaphtho[2,1,8-hij]isoquinoline-3-carboxylic acid ethyl ester; 4-Chloro-1-azabenzo[h]quinoline-3-carboxylic acid ethyl ester; 4-Chloro-1-azabenz[h]isoquinoline-3-carboxylic acid ethyl ester; 4-Chloro-BQCA ethyl ester; 4-Cl-BQCA-OEt
EINECS	Contact for details

Quality Control

Our production of Benzo[H]Quinoline-3-Carboxylic Acid, 4-Chloro-, Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.