Description

8-Bromo-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one is a versatile brominated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique benzodiazepine core, which provides a privileged scaffold for constructing complex molecules with targeted biological activity. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzodiazepine-based drug candidates, potentially for central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: The bromine atom offers a reactive site for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & R&D: Serves as a standard or starting material in university and corporate research laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	8-Bromo-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one
CAS No.	37040-46-3
Molecular Formula	C9H9BrN2O
Molecular Weight	241.09 g/mol
Synonyms	8-Bromo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one; 8-Bromo-1,5-benzodiazepin-2(3H)-one, 1,3,4,5-tetrahydro-; 8-Bromo-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one; 8-Bromotetrahydro-1,5-benzodiazepin-2-one; 37040-46-3; 8-Bromo-1,5-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.