Description

8-Methyl-4-Oxo-6-(m-Tolyl)-1,4-Dihydrocinnoline-3-Carboxylic Acid is a high-purity, synthetically derived cinnoline derivative, a class of nitrogen-containing heterocyclic compounds known for their versatile biological activity. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a valuable scaffold in medicinal chemistry research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Organic Synthesis Reagent: Employed in complex organic synthesis for constructing fused heterocyclic systems with potential biological relevance.
• Biochemical Tool Compound: Used in vitro and in vivo studies to investigate biological mechanisms and identify new therapeutic targets.

Basic Information

Product Name	8-Methyl-4-Oxo-6-(m-Tolyl)-1,4-Dihydrocinnoline-3-Carboxylic Acid
CAS No.	36991-83-0
Molecular Formula	C₁₇H₁₄N₂O₃
Molecular Weight	294.31 g/mol
Synonyms	6-(3-Methylphenyl)-8-methyl-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid; 8-Methyl-6-(3-methylphenyl)-1,4-dihydro-4-oxocinnoline-3-carboxylic acid; 6-(m-Tolyl)-8-methyl-1,4-dihydro-4-oxocinnoline-3-carboxylic acid; 36991-83-0; Cinnoline-3-carboxylic acid, 1,4-dihydro-8-methyl-4-oxo-6-(3-methylphenyl)-; 8-Methyl-4-oxo-6-(3-methylphenyl)-1,4-dihydrocinnoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Methyl-4-Oxo-6-(m-Tolyl)-1,4-Dihydrocinnoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports its use in GMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.