Description

Alanine, n-Acetyl-2-Mercapto- (9Ci) is a specialized, sulfur-containing derivative of alanine, featuring an acetyl-protected amino group and a reactive mercapto moiety. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel compounds, including peptide mimetics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the thiol group is critical for activity or binding.
• Peptidomimetic Research: Serves as a non-natural amino acid building block for creating peptide analogs with enhanced stability, bioavailability, or specific biological functions.
• Bioconjugation Chemistry: The reactive mercapto (-SH) group enables site-specific conjugation to maleimides or other electrophiles, useful for labeling proteins, antibodies, or creating antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Used in the development of activity-based probes or inhibitors to study cysteine protease enzymes and other thiol-dependent biological processes.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with unique redox or metal-chelating properties.

Basic Information

Product Name	Alanine, n-Acetyl-2-Mercapto- (9Ci)
CAS No.	36871-62-2
Molecular Formula	C5H9NO3S
Molecular Weight	163.19 g/mol
Synonyms	N-Acetyl-2-mercaptoalanine; 2-(Acetylamino)-3-mercaptopropanoic acid; 3-Mercapto-N-acetylalanine; N-Acetyl-3-mercaptoalanine; S-Acetyl-3-mercaptoalanine (common misnomer); NSC 163063; Alanine, N-acetyl-3-mercapto-; 2-Acetamido-3-mercaptopropionic acid
EINECS	Contact for details

Quality Control

Our Alanine, n-Acetyl-2-Mercapto- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and chiral purity where applicable. Our quality commitment supports GMP-oriented applications and research requiring high reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation of the mercapto group. The container should be kept in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.