Description

2-Deoxy-α-D-Ribofuranose is a fundamental deoxy sugar derivative, serving as a critical building block in nucleoside and nucleotide chemistry. Its primary commercial value lies in its role as a key intermediate for the synthesis of antiviral and anticancer pharmaceuticals, where precise stereochemistry is paramount. This high-purity compound is essential for research and production in pharmaceutical development, biotechnology, and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of nucleoside analogs used as antiviral (e.g., for HIV, hepatitis) and anticancer agents.
• Biochemical Research: Used in enzymatic studies, metabolic pathway analysis, and as a substrate or inhibitor in glycoscience research.
• Oligonucleotide Synthesis: Serves as a building block for modified DNA/RNA strands in diagnostic kits and therapeutic oligonucleotides.
• Glycochemistry: Employed in the synthesis of complex carbohydrates, glycoconjugates, and glycomimetics for drug discovery.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Development: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring deoxyribose motifs.

Basic Information

Product Name	2-Deoxy-α-D-Ribofuranose
CAS No.	36792-87-7
Molecular Formula	C5H10O4
Molecular Weight	134.13 g/mol
Synonyms	2-Deoxy-D-ribose; 2-Deoxy-D-erythro-pentose; D-2-Deoxyribose; 2-Desoxy-D-ribose; 2-Deoxy-D-ribofuranose; α-D-2-Deoxyribofuranose; D(-)-2-Deoxyribose; Thyminose
EINECS	Contact for details

Quality Control

Our 2-Deoxy-α-D-Ribofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available upon request, ensuring compliance with cGMP and relevant pharmacopeial guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range upon request
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.