Description

2,4-Dichloro-6,7,8-Trimethoxyquinazoline is a high-purity, multi-functional quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its versatile halogenated and methoxylated structure, which enables precise molecular construction for complex target molecules. This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline-based pharmaceuticals.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its halogenated quinazoline core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for the synthesis of organic electronic materials and advanced polymers with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	2,4-Dichloro-6,7,8-Trimethoxyquinazoline
CAS No.	36476-14-9
Molecular Formula	C₁₁H₁₀Cl₂N₂O₃
Molecular Weight	289.11 g/mol
Synonyms	6,7,8-Trimethoxy-2,4-dichloroquinazoline; 2,4-Dichloro-6,7,8-trimethoxyquinazoline; Quinazoline, 2,4-dichloro-6,7,8-trimethoxy-; 36476-14-9; 2,4-Dichloro-6,7,8-trimethoxy-quinazoline
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6,7,8-Trimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.