Description

3-Amino-3-(2,3-Dimethoxyphenyl)Propanoic Acid Hydrochloride is a high-purity, non-natural amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring both an amino acid backbone and a dimethoxyphenyl moiety, which makes it indispensable for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas requiring sophisticated chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• Peptidomimetic Chemistry: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Asymmetric Synthesis: Serves as a starting material or chiral auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or molecular probes for studying biological pathways and target engagement.
• Academic Research: A valuable reagent for universities and research institutes focusing on synthetic methodology and the development of new heterocyclic compounds.

Basic Information

Product Name	3-Amino-3-(2,3-Dimethoxyphenyl)Propanoic Acid Hydrochloride
CAS No.	36412-23-4
Molecular Formula	C11H16ClNO4
Molecular Weight	261.70 g/mol
Synonyms	3-Amino-3-(2,3-dimethoxyphenyl)propionic acid hydrochloride; β-Amino-2,3-dimethoxyhydrocinnamic acid hydrochloride; (R/S)-3-Amino-3-(2,3-dimethoxyphenyl)propanoic acid HCl; 2,3-Dimethoxy-β-alanine, 3-phenyl-, hydrochloride; 3-(2,3-Dimethoxyphenyl)-3-aminopropanoic acid hydrochloride; DL-3-Amino-3-(2,3-dimethoxyphenyl)propionic acid hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-3-(2,3-Dimethoxyphenyl)Propanoic Acid Hydrochloride is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development use under current Good Manufacturing Practice (cGMP) principles where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if specified), and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.