Description

2'-(2,3,4-Trihydroxybenzyl)-L-Serinohydrazide Hydrochloride is a specialized organic compound that serves as a key synthetic intermediate and building block in advanced chemical synthesis. Its unique molecular structure, featuring a trihydroxybenzyl group coupled with a serine hydrazide moiety, makes it valuable for constructing complex molecules with specific biological or chemical functionalities. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, peptide mimetic research, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the research and development of new drug candidates, particularly in areas requiring complex molecular architectures.
• Medicinal Chemistry Research: Used in the synthesis of peptide analogs and enzyme inhibitors for biological activity screening and structure-activity relationship (SAR) studies.
• Bioconjugation Chemistry: The hydrazide functional group enables its use as a linker for conjugating molecules to proteins, antibodies, or other biomolecules in diagnostic or therapeutic agent development.
• Chemical Biology Probes: Serves as a precursor for synthesizing molecular probes to study biological pathways and enzyme functions.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental organic synthesis projects and the exploration of new chemical methodologies.
• Fine Chemical Synthesis: Used in the multi-step synthesis of other high-value, complex fine chemicals and specialty materials.

Basic Information

Product Name	2'-(2,3,4-Trihydroxybenzyl)-L-Serinohydrazide Hydrochloride
CAS No.	36318-70-4
Molecular Formula	C₁₁H₁₆N₃O₅ • HCl
Molecular Weight	307.72 g/mol (Free base: 270.26 g/mol)
Synonyms	L-Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, hydrochloride; 2'-(2,3,4-Trihydroxybenzyl)-L-serine hydrazide hydrochloride; (2S)-2-Amino-3-hydroxy-2-[(2,3,4-trihydroxyphenyl)methyl]hydrazinepropanoic acid hydrochloride; Serinohydrazide, 2'-(2,3,4-trihydroxybenzyl)-, hydrochloride, L-; 36318-70-4; THB-SerHz • HCl
EINECS	Contact for details

Quality Control

Our production of 2'-(2,3,4-Trihydroxybenzyl)-L-Serinohydrazide Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance needs for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.