Description

6-Fluoro-4-Hydroxy-Quinoline-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring both a carboxylic acid and a hydroxyl group on the quinoline core, makes it a critical intermediate for creating complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical developers for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinolone-based antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Development: Used in research for creating new herbicides and fungicides, leveraging its bioactive quinoline scaffold.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Investigated for the development of organic ligands in metal-organic frameworks (MOFs) or functional materials due to its chelating properties.

Basic Information

Product Name	6-Fluoro-4-Hydroxy-Quinoline-2-Carboxylic Acid
CAS No.	36303-26-1
Molecular Formula	C₁₀H₆FNO₃
Molecular Weight	207.16 g/mol
Synonyms	6-Fluoro-4-hydroxy-2-quinolinecarboxylic acid; 2-Quinolinecarboxylic acid, 6-fluoro-4-hydroxy-; 6-Fluoro-4-hydroxyquinoline-2-carboxylic acid; 4-Hydroxy-6-fluoroquinoline-2-carboxylic acid; 6-Fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid; 6-Fluoro-4-hydroxy-1H-quinoline-2-carboxylic acid; 6-Fluoro-4-hydroxy-2-quinoline carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Hydroxy-Quinoline-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.