Description

N,N'-Dicyclohexylcarbodiimide Methiodide is a specialized quaternary ammonium salt derivative of the widely used coupling agent DCC (N,N'-Dicyclohexylcarbodiimide). This compound is valued for its role as a potent dehydrating agent and catalyst in complex organic synthesis, particularly in peptide coupling and esterification reactions where its enhanced reactivity and solubility profile are advantageous. It is a critical reagent for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for constructing complex molecular architectures.

Application

• Peptide Synthesis: Employed as a coupling reagent for the formation of peptide bonds, especially in challenging or sterically hindered sequences.
• Esterification & Amidation: Acts as a powerful dehydrating agent to facilitate the condensation of carboxylic acids with alcohols or amines.
• Pharmaceutical Intermediate Manufacturing: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Synthesis: Applied in the production of certain herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Utilized as a catalyst or additive in the synthesis of specialty polymers and polyurethanes.
• Bioconjugation: Facilitates the linking of biomolecules, such as proteins or peptides, to other molecules or surfaces for diagnostic and therapeutic applications.
• Academic & Industrial R&D: A staple reagent in research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	N,N'-Dicyclohexylcarbodiimide Methiodide
CAS No.	36049-77-1
Molecular Formula	C15H27IN2
Molecular Weight	362.30 g/mol
Synonyms	DCC Methiodide; N,N'-Dicyclohexylcarbodiimide Methyl Iodide; 1-Cyclohexyl-3-(cyclohexylcarbamimidoyl)-1-methylimidazol-3-ium Iodide; Dicyclohexylcarbodiimide Methyl Iodide; DCC-Methiodide; DCCMI; Carbodiimide, dicyclohexyl-, methiodide; Methyliodide adduct of DCC
EINECS	Contact for details

Quality Control

Our N,N'-Dicyclohexylcarbodiimide Methiodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.