Description

3,5-Xylyl Chloroformate is a specialized organic reagent belonging to the chloroformate ester class, identified by CAS No. 36037-36-2. This compound is a critical building block in advanced organic synthesis, valued for its role as a versatile acylating and protecting agent. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the 3,5-dimethylbenzyloxycarbonyl (Dmz) protecting group.
• Peptide Synthesis: Used as a coupling agent or for the temporary protection of amine groups during solid-phase and solution-phase peptide synthesis.
• Agrochemical Production: Serves as a precursor in the manufacture of certain herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Employed in the modification of polymers and the synthesis of polycarbonates or other specialty polymers with specific functional groups.
• Chemical Research: A valuable tool in academic and industrial R&D for constructing complex molecular architectures and exploring new synthetic methodologies.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized dyes and organic pigments.

Basic Information

Product Name	3,5-Xylyl Chloroformate
CAS No.	36037-36-2
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	3,5-Dimethylbenzyl Chloroformate; Chloroformic Acid 3,5-Dimethylbenzyl Ester; (3,5-Dimethylphenyl)methyl Carbonochloridate; 3,5-Dimethylbenzyloxycarbonyl Chloride; Dmz-Cl; 36037-36-2; Carbonochloridic Acid (3,5-Dimethylphenyl)methyl Ester
EINECS	Contact for details

Quality Control

Our 3,5-Xylyl Chloroformate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a recommended temperature of 2-8°C. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.