Description

tert-Butyl n-Hydroxycarbamate is a versatile organic compound primarily utilized as a key synthetic intermediate and protecting group reagent. Its value lies in its ability to introduce the tert-butoxycarbonyl (Boc) group onto hydroxylamines, a critical step in the synthesis of complex molecules, particularly in pharmaceutical research. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing hydroxamic acid or hydroxylamine functionalities.
• Protecting Group Reagent: Used to introduce the acid-labile tert-butoxycarbonyl (Boc) protecting group onto hydroxylamines, facilitating multi-step synthetic sequences.
• Agrochemical Synthesis: Serves as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Peptide & Protein Research: Employed in the modification and protection of amino acid side chains during peptide synthesis.
• Metal Chelator Precursor: Used in the preparation of ligands and chelating agents for catalytic and analytical applications.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialized polymers and coatings.

Basic Information

Product Name	tert-Butyl n-Hydroxycarbamate
CAS No.	36016-38-3
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	N-(tert-Butoxycarbonyl)hydroxylamine; Boc-hydroxylamine; tert-Butyloxycarbonylhydroxylamine; O-(tert-Butoxycarbonyl)hydroxylamine; BOC-NHOH; N-Boc-hydroxylamine; tert-Butyl N-hydroxycarbamate; Carbamic acid, N-hydroxy-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-Hydroxycarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	85 - 90 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.