Description

6-Chloro-2-(Trifluoromethyl)Quinazolin-4(3H)-One is a high-value, halogenated quinazolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinazolinone core.
• Material Science: Serves as a building block for advanced organic materials, including liquid crystals, organic semiconductors, and specialty polymers.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex molecular libraries and exploring novel chemical reactions.
• Fluorinated Compound Synthesis: The trifluoromethyl group provides a valuable handle for introducing fluorine atoms, enhancing metabolic stability and lipophilicity in target molecules.

Basic Information

Product Name	6-Chloro-2-(Trifluoromethyl)Quinazolin-4(3H)-One
CAS No.	35982-55-9
Molecular Formula	C9H4ClF3N2O
Molecular Weight	248.59 g/mol
Synonyms	6-Chloro-2-(trifluoromethyl)-3,4-dihydroquinazolin-4-one; 6-Chloro-2-(trifluoromethyl)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 6-chloro-2-(trifluoromethyl)-; 35982-55-9; 6-Chloro-2-trifluoromethylquinazolin-4(3H)-one; 2-Trifluoromethyl-6-chloro-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2-(Trifluoromethyl)Quinazolin-4(3H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.