Description

6-Bromo-2-(Trifluoromethyl)Quinazolin-4(3H)-One is a high-value, multifunctional heterocyclic building block characterized by its bromo and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by leveraging the bioactivity of the quinazolinone core.
• Material Science: Serves as a building block for advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: The bromine atom provides an excellent handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	6-Bromo-2-(Trifluoromethyl)quinazolin-4(3H)-one
CAS No.	35982-47-9
Molecular Formula	C9H4BrF3N2O
Molecular Weight	293.04 g/mol
Synonyms	6-Bromo-2-(trifluoromethyl)-4(3H)-quinazolinone; 6-Bromo-2-trifluoromethyl-3H-quinazolin-4-one; 4(3H)-Quinazolinone, 6-bromo-2-(trifluoromethyl)-; 35982-47-9; 6-Bromo-2-(trifluoromethyl)quinazolin-4-ol; 6-Bromo-2-trifluoromethylquinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(Trifluoromethyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.