Description

Ethyl 8-Bromo-4-Hydroxyquinoline-3-Carboxylate is a versatile and high-purity quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated hydroxyquinoline structure makes it a valuable building block for constructing complex molecules with potential biological activity. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive quinoline core.
• Coordination Chemistry & Ligand Synthesis: Serves as a chelating ligand precursor for metal complexes used in catalysis or imaging.
• Material Science: Building block for organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Ethyl 8-Bromo-4-Hydroxyquinoline-3-Carboxylate
CAS No.	35975-57-6
Molecular Formula	C₁₂H₁₀BrNO₃
Molecular Weight	296.12 g/mol
Synonyms	8-Bromo-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 8-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate; 8-Bromo-4-hydroxy-3-quinolinecarboxylic Acid Ethyl Ester; 3-Carbethoxy-8-bromo-4-hydroxyquinoline; 1,4-Dihydro-8-bromo-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 8-Bromo-4-hydroxy-1H-quinoline-3-carboxylic acid ethyl ester; 35975-57-6; Ethyl 8-bromo-4-hydroxyquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 8-Bromo-4-Hydroxyquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.