Description

4-Hydroxy-Benzo[H]Quinoline-3-Carboxylic Acid is a high-purity, multifunctional heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused quinoline structure with both phenolic and carboxylic acid functionalities makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways, due to its bioactive quinoline scaffold.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, where its structure contributes to bioactivity and selectivity.
• Ligand and Chelating Agent: Serves as a starting material for synthesizing specialized ligands used in catalysis, metal extraction, and analytical chemistry applications.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast organic dyes and pigments, especially azo dyes and fluorescent markers.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) for electronic and sensing devices.
• Chemical Reference Standard: Supplied as a certified reference material (CRM) for analytical method development, validation, and quality control in regulatory testing laboratories.

Basic Information

Product Name	4-Hydroxy-Benzo[H]Quinoline-3-Carboxylic Acid
CAS No.	35957-14-3
Molecular Formula	C₁₄H₉NO₃
Molecular Weight	239.23 g/mol
Synonyms	4-Hydroxybenzo[h]quinoline-3-carboxylic acid; 3-Carboxy-4-hydroxybenzo[h]quinoline; 4-Hydroxy-1-azanaphthalene-3-carboxylic acid; Benzo[h]quinoline-3-carboxylic acid, 4-hydroxy-; 4-Hydroxybenzo(h)quinoline-3-carboxylic acid; 4-OH-BQCA
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-Benzo[H]Quinoline-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.