Description

5β-Iodo-2α-Methyl-1,3-Dioxane is a specialized iodinated dioxane derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a reactive iodine atom on the dioxane ring, makes it a valuable precursor for constructing complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and development of new drug candidates, particularly for introducing iodine or modifying stereochemistry.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides where the iododioxane moiety can impart specific biological activity.
• Organic Synthesis Building Block: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to form new carbon-carbon and carbon-heteroatom bonds.
• Material Science Research: Employed in the synthesis of functionalized polymers or ligands for catalytic systems.
• Academic & Industrial R&D: A valuable tool for methodological studies and exploring new synthetic pathways in chemistry laboratories worldwide.

Basic Information

Item	Details
Product Name	5β-Iodo-2α-Methyl-1,3-Dioxane
CAS No.	35878-02-5
Molecular Formula	C5H9IO2
Molecular Weight	228.03 g/mol
Synonyms	5-Iodo-2-methyl-1,3-dioxane (β-iodo, α-methyl isomers); 2-Methyl-5-iodo-1,3-dioxane; (2R,5R)-5-Iodo-2-methyl-1,3-dioxane; (2S,5S)-5-Iodo-2-methyl-1,3-dioxane; 1,3-Dioxane, 5-iodo-2-methyl-; Iodomethyl dioxane derivative
EINECS	Contact for details

Quality Control

Our 5β-Iodo-2α-Methyl-1,3-Dioxane is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical 97-99%)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.