Description

Carboxymefloquine is a key chemical intermediate and derivative of the antimalarial drug mefloquine. This compound is essential for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents and the study of drug metabolites. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in advanced medicinal chemistry and API development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of mefloquine derivatives and related antimalarial compounds.
• Active Pharmaceutical Ingredient (API) Research: Used in R&D for developing new drug candidates and studying structure-activity relationships.
• Metabolite Standard: Serves as a reference standard in analytical laboratories for pharmacokinetic and metabolic studies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized organic molecules.
• Biochemical Research: Utilized in academic and industrial research to investigate biological pathways and mechanisms of action.

Basic Information

Product Name	Carboxymefloquine
CAS No.	35853-50-0
Molecular Formula	C18H16F6N2O3
Molecular Weight	422.32 g/mol
Synonyms	DL-Carboxymefloquine; Mefloquine Carboxylic Acid; (±)-erythro-α-(2-Piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol-4-carboxylic Acid; 2,8-Bis(trifluoromethyl)-4-quinolinecarboxylic Acid, α-(2-Piperidinyl)-, (αR)-; Mefloquine-4-carboxylic Acid; Lariam Carboxylic Acid Metabolite; WR 184,806 Carboxylic Acid
EINECS	Contact for details

Quality Control

Our Carboxymefloquine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.