Description

2,8-Bis(Trifluoromethyl)-4-Bromoquinoline is a high-value, multi-functional halogenated quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and specialty chemical building block, prized for its unique molecular architecture. It is primarily utilized by R&D and manufacturing teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the quinoline and trifluoromethyl groups contribute to biological activity and metabolic stability.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in transition metal catalysis for cross-coupling and other organic transformations.
• Fluorinated Compound Library: An essential building block for medicinal chemistry research in constructing diverse fluorinated compound libraries for high-throughput screening.

Basic Information

Product Name	2,8-Bis(Trifluoromethyl)-4-Bromoquinoline
CAS No.	35853-45-3
Molecular Formula	C₁₂H₄BrF₆N
Molecular Weight	356.06 g/mol
Synonyms	4-Bromo-2,8-bis(trifluoromethyl)quinoline; 2,8-Bis(trifluoromethyl)-4-bromoquinoline; Quinoline, 4-bromo-2,8-bis(trifluoromethyl)-; 4-Bromo-2,8-di(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 2,8-Bis(Trifluoromethyl)-4-Bromoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.