Description

Methyl 2-(S)-[n-Carbobenzyloxy]Amino-3-Aminopropionate, Hydrochloride is a protected amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a crucial chiral building block for the construction of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including protease inhibitors and other bioactive molecules. The hydrochloride salt form enhances its stability and handling properties for synthetic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of inhibitors for enzymes like HIV protease and renin.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation: Employed in the preparation of labeled peptides or peptide-drug conjugates for diagnostic and therapeutic purposes.
• Chemical Biology Probes: Utilized to create modified peptides for studying protein-protein interactions and cellular pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	Methyl 2-(S)-[n-Carbobenzyloxy]Amino-3-Aminopropionate, Hydrochloride
CAS No.	35761-27-4
Molecular Formula	C12H17ClN2O4
Molecular Weight	288.73 g/mol
Synonyms	Methyl (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-aminopropanoate hydrochloride; (S)-Methyl 3-amino-2-((((benzyloxy)carbonyl)amino))propanoate hydrochloride; Z-Dap-OMe·HCl; Cbz-Dap-OMe·HCl; Nα-Cbz-L-2,3-diaminopropionic acid methyl ester hydrochloride; Methyl N2-[(benzyloxy)carbonyl]-L-2,3-diaminopropanoate hydrochloride; Methyl 2-(S)-[N-Carbobenzyloxy]Amino-3-Aminopropionate Hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-(S)-[n-Carbobenzyloxy]Amino-3-Aminopropionate, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing specific results for identity, assay, and purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.